Un avance científico que debe ser reconocido por todo el mundo.
Eva Ramón Gallegos, científica de la Escuela Nacional de Ciencias Biológicas (ENCB) del Instituto Politécnico Nacional (IPN), logró eliminar en un 100 por ciento el Virus del Papiloma Humano (VPH), focalizado en el cérvix uterino de 29 mujeres de la Ciudad de México a través de una terapia fotodinámica.
En un comunicado, el IPN informó que las pacientes fueron tratadas con terapia fotodinámica, una técnica no invasiva, la cual puede ser un m
Ramón Gallegos explicó que la terapia fotodinámica, además de erradicar al VPH (agente patógeno que es la principal causa de cáncer cérvicouterino), también elimina lesiones premalignas de cáncer de cérvix en una etapa muy inicial, como se comprobó en un estudio piloto.
La doctora detalló que la terapia fotodinámica consiste en aplicar en el cuello del útero un fármaco llamado ácido delta aminolevulínico, que después de cuatro horas se transforma en protoporfirina IX, sustancia química fluorescente que se acumula en las células dañadas, lo cual permite eliminar con un rayo láser especial, únicamente las estructuras impregnadas con ésta.
La investigadora, quien a lo largo de dos décadas ha estudiado el efecto de la terapia fotodinámica en distintas neoplasias (melanoma, cáncer de mama y cérvicouterino), precisó que en la fase clínica se han tratado con esta terapia 420 pacientes de Oaxaca y Veracruz, además de las 29 de la Ciudad de México, quienes estaban infectadas con el VPH, y presentaban lesiones premalignas en el cérvix o tenían ambas afecciones.
Ramón Gallegos mencionó que el tratamiento se realizó en dos etapas bajo dos esquemas diferentes de aplicación de la terapia.
“En la primera parte, en la que participaron las mujeres de Oaxaca y Veracruz, los resultados fueron alentadores. En la aplicación de la técnica en las capitalinas también tuvo un efecto muy esperanzador, lo que abre la posibilidad de hacer más eficaz el tratamiento, al usar el esquema que se adapte a la situación de las pacientes”, dijo.
En la primera parte de la investigación, se aplicó el tratamiento en tres ocasiones con un intervalo de 48 horas cada una, con un tiempo de radiación acorde a cada caso y el tipo de lesión. Se realizaron revisiones y se repitieron los estudios de diagnóstico.
Los resultados fueron los siguientes: en las personas que solo tenían el virus sin lesiones, se logró eliminar el VPH en el 85 por ciento; en las pacientes que tenían VPH con lesiones tuvo una eficacia del 85 por ciento, y de quienes tenían lesiones sin VPH se tuvo éxito en 42 por ciento.
La investigadora del IPN indicó que a las mujeres de la Ciudad de México se les aplicó el doble de la concentración de ácido delta aminolevulínico. El tratamiento se realizó dos ocasiones con intervalo de 48 horas.
También efectuaron las revisiones y los estudios de diagnóstico. Los resultados fueron los siguientes: se logró eliminar el VPH en el 100 por ciento de las pacientes que lo portaban sin tener lesiones, 64.3 por ciento en las mujeres con VPH y lesiones, y el 57.2 por ciento en quienes presentaban lesiones sin VPH.
Comentó que la terapia fotodinámica es segura y libre de efectos secundarios. “A diferencia de otros tratamientos únicamente elimina las células dañadas y no incide sobre las estructuras sanas. Por ello, tiene gran potencial para disminuir el índice de mortandad por cáncer cervicouterino”, enfatizó.
La doctora Eva Ramón Gallegos consiguió estos avances gracias a la colaboración de Elizabeth Maldonado Alvarado y María Teresa López Cárdenas, Alejandro Martínez Escobar, Araceli Espinosa Montesinos, Adriana Jiménez Hernández, Martha Olivia Osorio Peralta, Alejandra Moreno Vázquez y Lydia Alejandra Martínez Guzmán.
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este procedimiento se practica en todas las instituciones ya?
Hola, tengo una hermana que padece esta enfermedad y se siente desauciada con deprecion, me interesa información para buscar ayuda o de que manera tratarla con este método en alguna dependencia, se lo agradecería mucho 🙏
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